Mesenchymal stem cells (MSCs) are an effective treatment for lupus due to their immune modulatory effects. The immune system of lupus patients is overactive, which leads to inflammation and autoimmune attacks on healthy tissue. MSCs are able to down-regulate inflammation and diminish autoimmune responses by interacting with immune cells, including T cells, B cells, and dendritic cells.
Research has shown that MSCs have the ability to inhibit the proliferation of T cells and promote regulatory T cells, which play a critical role in limiting autoimmunity. MSCs have also been shown to decrease the production of autoantibodies, which are antibodies that attack healthy tissues in lupus patients.
In addition, MSCs have been shown to promote tissue repair and regeneration, which is important in lupus patients who may experience damage to various organs and tissues.
MSCs work for lupus by enhancing immune regulation, suppressing inflammation, reducing autoantibody production, and promoting tissue repair.
