Mesenchymal stem cells (MSCs) have the ability to regulate the immune system and reduce inflammation, making them a potentially effective treatment for rheumatoid arthritis. Immunomodulation is a key factor in how the stem cells work for RA treatment.
When administered, MSCs can home to sites of inflammation and release anti-inflammatory molecules such as cytokines and growth factors. This can help to reduce swelling, pain, and joint damage caused by the immune response.
Additionally, MSCs have been shown to modulate the activity of immune cells, such as T cells and B cells, by suppressing their activation and proliferation, and promoting the generation of regulatory T cells.
Overall, the mechanisms by which MSCs work in rheumatoid arthritis involve both direct and indirect effects on the immune system and local tissue repair processes. The therapeutic effects of MSCs for rheumatoid arthritis are incredible. They will help reprogram the immune system and regenerate deteriorating cartilage with peak results typically seen 3 to 6 months post treatment.
